Description
How it works
Novapressin Injection 1 mg 1 Vial acts on receptors in the kidney to retain water in the body, which helps to prevent excessive loss of water in the urine.
Side effects
Major & minor side effects for Novapressin Injection 1 mg 1 Vial
- Headache
- Abdominal cramps
- Nausea
- Diarrhea
- Pale skin
- Chest pain
- Shortness of breath
- Vomiting
- Irregular heartbeat
- Increased blood sugar levels rare
Uses of Novapressin Injection 1 mg 1 Vial
What is it prescribed for?
- Bleeding Esophageal VaricesThis medicine is used to treat the bleeding of dilated blood vessels of the esophagus which develops when the blood flow to the liver is reduced due to a blood clot within the liver or scar tissue.
- Type 1 Hepatorenal SyndromeThis medicine is used in the treatment of type 1 hepatorenal syndrome (progressive kidney failure in people with severe liver damage) characterized by rapid kidney failure and an increase in the levels of creatinine.
Concerns
Frequently asked questions
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Onset of action
The amount of time required for this medicine to show its action is not clinically established.
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Duration of Effect
The amount of time for which this medicine remains active in the body is not clinically established.
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Safe with Alchohol?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
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Is it habit forming?
No habit-forming tendencies were reported.
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Usage in pregnancy?
This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
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Usage while breast-feeding?
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
When not to use?
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Allergy
This medicine is not recommended for use in patients with a known allergy to Novapressin Injection 1 mg 1 Vial or any other inactive ingredients present along with it.
Warnings
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Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
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Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
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Septic shock
This medicine should be used with extreme caution in patients with septic shock due to the increased risk of worsening of the patient’s condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
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Chronic kidney impairment
This medicine should be used with extreme caution in patients with an impaired kidney function due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
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Heart disorders
This medicine should be used with caution in patients with heart disorders such as arrhythmias, acute coronary syndrome, or recent myocardial infarction, etc due to the increased risk of worsening of the patient’s condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
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Cerebral or peripheral vascular disorders
This medicine should be used with caution in patients with cerebral or peripheral vascular disorders due to the increased risk of worsening of the patient’s condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
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Use in elderly
This medicine should be used with caution in patients aged above 70 years due to the increased risk of adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
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Use in children
This medicine is not recommended for use in children below 18 years of age since the safety and efficacy of use are not clinically established.
Dosage
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Missed Dose
Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of a missed dose is very less.
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Overdose
Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
Interactions
Interaction with Medicines
- Aliskiren
- antihistamines
- Propofol
- Erythromycin
- Tricyclic Antidepressants
- Class IA & III Antiarrythmic agents
General Instructions
This medicine should be administered by a qualified healthcare professional. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine.
Other details
- Usage does not depend on food timings
- To be taken as instructed by doctor
- Does not cause sleepiness
References
- drugbank.ca – Terlipressin [Internet]. Available from: https://www.drugbank.ca/drugs/DB02638 [cited 11/9/2020]. 2020
How to use Novapressin Injection 1 mg 1 Vial
Administered by IV bolus injection.
Stability: Frozen dried powder and the diluent may be stored at room temperature, protected from direct sunlight. Reconstituted solution should be used within 12 hours.
UNLICENSED USE
Children: Adjunct in acute massive haemorrhage of GI tract or oesophageal varices: IV. 12-18 yr, 2 mg every 4 hr until bleeding controlled (after initial dose, may reduce to 1 mg every 4 hr if not tolerated or body-weight under 50 kg), max duration 48 hr.
what are the adverse effects of Novapressin Injection 1 mg 1 Vial?
Abdominal cramps, headache, transient blanching, hypertension.
What happens if I miss a dose of Novapressin Injection 1 mg 1 Vial?
Adults: 2 mg IV bolus injection, followed by 1 mg or 2 mg every 4 to 6 hr up to max 72 hr. Children: Not recommended.
One of the following licensed pharmacy from the nearest location will deliver Novapressin Injection 1 mg 1 Vial. The details of the licensed pharmacy shall be shared once you request the drugs and the respective pharmacy accepts your request based on valid prescription and availability.
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