Description
Angiotensin II Receptor Blocker. Losartan selectively and competitively blocks angiotensin II receptors at the AT1 receptor site, this mechanism results in a compensatory increase in levels of renin and angiotensin. This drug binds with AT1 receptors with high affinity and is more than 10000 fold selective for the AT1 receptor than the AT2 receptor.
Ingredients
Losartan potassium
Uses
Losartan Potassium is utilized for the following therapeutic indications:
- Management of hypertension
- Reduction of the risk of stroke in patients with hypertension and left ventricular hypertrophy
- Treatment of diabetic nephropathy in patients with type 2 diabetes
- Improvement of cardiovascular outcomes in patients with heart failure
- Treatment of patients with hypertension to prevent kidney damage
- Management of patients with hypertension who are intolerant to ACE inhibitors
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