Description
Famotidine is a drug that acts as a competitive histamine H-receptor antagonist (H2RA) it binds to the H-receptors that are located on the basolateral membrane of the parietal cell in the stomach; in this way it effectively blocks histamine actions. Its pharmacologic actions lead to the inhibition of gastric secretion by suppressing acid concentration and volume of gastric secretion. Famotidine inhibits both basal and nocturnal gastric acid secretion; it also decreases gastric volume, acidity, and secretion that are stimulated by food, caffeine, insulin, and pentagastrin(synthetic polypeptide that acts like gastrin).
Ingredients
Famotidine
Uses
Famotidine is utilized for the following therapeutic indications:
- Treatment of gastroesophageal reflux disease (GERD)
- Management of peptic ulcers
- Zollinger-Ellison syndrome
- Prevention of stress-induced mucosal disease
- Relief of heartburn and acid indigestion
- Erosive esophagitis due to acid reflux
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